Updated : Aug/07/2020 , NP
Note :
Always consult a qualified medical practitioner before taking any new medication
If you are using any information given on this page, please do so at your risk.
- This page is for my personal reference only due to the fact that there are many people amongst friends and family suffering from diabetes.
- This is a compilation of my readings through latest papers published over last 6 months.
Tech Note: This page is not seen by any search engines including google (I’ve technically instructed them to ignore this page).
1. Top Bookmarks for COVID-19 – click here
2. Can I get some testing kits for COVID-19 ? click here
3. Can I get COVID-19 infection again ? – click here
4. Type 2 Diabetes – आपसे नहीं होगा – click here
5. अगर आपको डायबिटीज है और साथ ही आपको लगता है कि आप Corona से संक्रमित है तो – click here
*COVID symptoms*
People with COVID-19 have had a wide range of symptoms reported – ranging from mild symptoms to severe illness.
Symptoms may appear *2-14 days after exposure to the virus*. People with these symptoms may have COVID-19:
*SOME DIGESTIVE PROBLEMS*
- Diarrhea
- Nausea or vomiting
*SOME RESPIRATORY / BREATHING PROBLEMS*
- Cough
- Congestion or runny nose
- Shortness of breath or difficulty breathing
- Sore throat
*SOME OF OTHER PROBLEMS*
- Fatigue / Tiredness
- Muscle or body aches
- Headache
- Fever
- Chills (feeling cold)
- New loss of taste or smell (usually for asymptomatic patients ; further studies needed. )
*Look for emergency warning signs for COVID-19*
If someone is showing any of these signs, seek emergency medical care immediately
- Trouble breathing
- Persistent pain or pressure in the chest
- New confusion
- Inability to wake or stay awake
- Bluish lips or face
*MUST KEEP THESE THINGS READY*
- Blood Pressure Measuring Machine
- Thermometer
- For diabetics, Glucometer with enough test-strips and lancets
- For diabetics, Recent A1C blood report
*FIRST LINE OF THERAPY* (Always consult a doctor before taking any medicine)
- Aziththromycin
- HydroxyChloriquin (not for diabetic patient taking glucose medicines)
*Top References for COVID-19 medication – *University of Liverpool*
Must check the drug interaction (reaction) if you are taking more than one medicine.
- *COVID Drug Interaction Online Checker(best viewed in large screens)* – https://www.covid19-druginteractions.org/checker
- *COVID Drug Interaction Online Reference* –
- *Top COVID Treatment Resources*
-
- Liverpool COVID-19 Interactions^ https://www.covid19-druginteractions.org/
- Should anti-diabetic medications be reconsidered amid COVID-19 pandemic?^ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151403/
HCQ alone gives meaningful control of glucose
- Potential Effect of Hydroxychloroquine in Diabetes Mellitus: A Systematic Review on Preclinical and Clinical Trial Studies^ https://www.hindawi.com/journals/jdr/2020/5214751/
Cautiously use Metformin with HCQ or CQ
*Abstract*
The new study was published online on scientific pre-print server BioRxiv and shows that 30-40% of mice treated with a combination of HCQ or CQ and diabetes drug metformin, died. Treatment with the same dose of either drug alone had no effect on the survival of the mice.
HCQ – HydroxyChloroquin
CQ – Chloroquin
*References* –
- Researchers Warn Possible Coronavirus Treatment Hydroxychloroquine May Be Toxic When Combined With Diabetes Drug^ https://www.forbes.com/sites/victoriaforster/2020/04/05/researchers-warn-that-covid-19-treatment-touted-by-trump-may-be-toxic-when-combined-with-diabetes-drug/#5808e26055f8
- A New Drug–Drug Interaction between Hydroxychloroquine and Metformin? A Signal Detection Study | SpringerLink^ https://link.springer.com/article/10.1007/s40264-020-00955-y
- Two potential COVID-19 treatments could be deadly when combined with metformin – Diabetes^ https://www.diabetes.co.uk/news/2020/apr/two-potential-covid-19-treatments-are-deadly-combined-with-metformin.html
- Fatal toxicity of chloroquine or hydroxychloroquine with metformin in mice | bioRxiv^ https://www.biorxiv.org/content/10.1101/2020.03.31.018556v1
- Drug interaction between hydroxychloroquine and metformin^ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290148/
- Potential Benefits and harms of Novel Anti-Diabetic drugs during COVID-19 Crisis
Read using Google –https://docs.google.com/viewer?url=https%3A%2F%2Fwww.mdpi.com%2F1660-4601%2F17%2F10%2F3664%2Fpdf&embedded=true&chrome=false&dov=1&urp=gmail_link
Download – https://www.mdpi.com/1660-4601/17/10/3664/pdf
*References for DPP-4 inhibitors, GLP1 receptor agonists, SGLT inhibitors*
Read using Google – https://docs.google.com/viewer?url=https%3A%2F%2Fwww.mdpi.com%2F1660-4601%2F17%2F10%2F3664%2Fpdf&embedded=true&chrome=false&dov=1
Download – https://www.mdpi.com/1660-4601/17/10/3664/pdf
Notable References: COVID-19
- COVID-19: How does Metformin interact with the new Coronavirus and why some persons are immune to it and others not?^https://www.researchgate.net/post/COVID-19_How_does_Metformin_interact_with_the_new_Coronavirus_and_why_some_persons_are_immune_to_it_and_others_not
- Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments – Lemaitre – – Fundamental & Clinical Pharmacology – Wiley Online Library^ https://onlinelibrary.wiley.com/doi/full/10.1111/fcp.12586
- SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done? | Immunity & Ageing | Full Text^ https://immunityageing.biomedcentral.com/articles/10.1186/s12979-020-00192-y
- A New Drug–Drug Interaction Between Hydroxychloroquine and Metformin? A Signal Detection Study | SpringerLink^ https://link.springer.com/article/10.1007/s40264-020-00955-y
- The University of the Philippines Hydroxychloroquine PEP Against COVID-19 Trial – Full Text View – ClinicalTrials.gov^ https://clinicaltrials.gov/ct2/show/NCT04364815
- Should anti-diabetic medications be reconsidered amid COVID-19 pandemic? – Diabetes Research and Clinical Practice^ https://www.diabetesresearchclinicalpractice.com/article/S0168-8227(20)30396-X/fulltext
All about Hydroxychloroquin ;
See interactions section categorized as Level 1 (Severe), Level 2 (Major), Level 3 (Moderate), Level 4 (Minor)*
https://covid-19.elsevier.health/en-US/drug-monographs/hydroxychloroquine
Type-2 Diabetes Medication Choices in Non-COVID times
- Diabetes Medication Choice^ https://diabetesdecisionaid.mayoclinic.org/app/diabetes?lang=EN&v=m
- Practice Tools^ https://www.diabeteseducator.org/practice/practice-tools
- Diabetes Medication Choice | Mayo Clinic Shared Decision Making National Resource Center^ https://shareddecisions.mayoclinic.org/decision-aid-information/decision-aids-for-chronic-disease/diabetes-medication-management/
- SGLT-2-Inhibitors-Chart ^ http://www.diabetesincontrol.com/wp-content/uploads/2020/06/SGLT-2-Inhibitors-Chart-06302020.pdf
- Type 2 diabetes – Diagnosis and treatment – Mayo Clinic^ https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/diagnosis-treatment/drc-20351199
- Tools – Diabetes In Control^ http://www.diabetesincontrol.com/tools-for-your-practice/
- SGLT-2 Inhibitor Chart^ http://www.diabetesincontrol.com/sglt-2-inhibitor-chart/
“*Diabetes Management Apps * “`
*Track your daily diabetes data – medication, sugar levels, exercise etc. and possibly predict your A1C*
- Diabetes:M – Management & Blood Sugar Tracker App – Apps on Google Play ^https://play.google.com/store/apps/details?id=com.mydiabetes&hl=en_US&showAllReviews=true
- mySugr – Diabetes App & Blood Sugar Tracker – Apps on Google Play ^https://play.google.com/store/apps/details?id=com.mysugr.android.companion&hl=en_US
- OneTouch Reveal® mobile app for Diabetes – Apps on Google Play ^https://play.google.com/store/apps/details?id=com.lifescan.reveal&hl=en_US
- Glucose Buddy Diabetes Tracker – Apps on Google Play ^https://play.google.com/store/apps/details?id=com.skyhealth.glucosebuddyfree&hl=en_US